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Chromatographic separation of these compounds was performed using L-colomn2 (Chemical Evaluation and Research Institute, Tokyo, Japan) with solvent A (0.1% formic acid in MQ water) and solvent B [0.1% formic acid in methanol (LC/MS grade, Fujifilm Wako Pure Chemical Corp.)] at a flow rate of 0.4 mL/min

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As an example, tendon tissue is composed primarily of tendon fibroblastic cells and extracellular matrix, which contains predominantly type I collagen, type III collagen and glycoproteins (Fukuta et al

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44 FilomeniG.AquilanoK.CivitarealeP.RotilioG.CirioloM

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Type II collagen synthesis: Cartilage-specific collagen differs from bone's type I collagen

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